Notes
Overview of Gastrointestinal Anatomy
Sections
Overview of Digestive Organ Anatomy
Overview
6 key functions of the digestive system:
- Ingestion of foods and liquids
- Digestion (chemical and mechanical) of foods and liquids
- Propulsion of materials through the body
- Secretion of digestive enzymes and hormones
- Absorption of nutrients and water from foods and liquids
- Elimination of wastes (aka feces)
Anatomical & Functional Divisions
- Gastrointestinal tract (aka, GI tract, alimentary canal, gut)
- Accessory organs
Anatomy & Physiology
GI tract:
Oral cavity (aka, mouth)
- Initiates digestion of foods and liquids
- Is bound anteriorly by the lips, opens posteriorly to the oropharynx.
Pharynx
- Open to the nasal cavity, the oral cavity, and the larynx because the pharynx is a common passageway for both the digestive and respiratory systems.
Esophagus
- Muscular tube that transports foods and liquids to the stomach.
Stomach
See: Stomach
- J-shaped pouch
- Where foods and liquids are stored and also converted to a thick, soup-like substance called chyme
- See: Physiology of Swallowing & Gastric Filling
Small Intestine
See: Small intestine
- Long tube that coils upon itself
- it's the primary site of nutrient absorption
- Its length increases contact with absorptive tissues, which optimizes nutrient absorption.
- Small intestine subdivisions:
— Duodenum, which is relatively short, and receives chyme from the stomach.
— Jejunum, which is the longer middle segment.
— Ileum, which is the terminal segment of the small intestine.
Large Intestine
See: Large intestine
- Primary site of water absorption.
- Large intestine subdivisions:
— Ascending colon, which ascends the right side of the abdomen.
— Transverse colon, which passes along the transverse plane of the body.
— Descending colon, which descends the left side of the abdomen.
— The sigmoid colon, which is the S-shaped (aka, sigmoid) portion of the colon within the pelvis.
— Cecum, which is a small, pouch-like structure.
— Vermiform appendix extends from the cecum; this wormlike (aka, "vermiform") structure houses lymphoid tissue.
— Rectum is the distal-most portion of the large intestine and receives the sigmoid colon.

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Anus
- Terminal end of the GI tract – where wastes exit.
Sphincters
- Muscular rings that regulate the movement of materials through the GI tract.
Accessory organs
- Teeth, which mash the food
- Tongue, which shapes food into a "bolus"
- Salivary glands, which produce saliva
— Parotid, the largest, lies in the cheek
— Sublingual lies under the tongue ("lingual" refers to the tongue)
— Submandibular lies below the mandible - Liver produces the bile
- Gallbladder stores and secretes bile
- Pancreas produces enzyme-rich pancreatic juice.
- Ducts connect the liver, gallbladder, and pancreas to the duodenum, which receives bile and pancreatic juices to the duodenum.
CT Scans

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For more, see our Abdominal CT Scan Atlas on the Course Page
Supplemental Materials
Drawing Highlight
Clinical Correlations
- Gastric reflux occurs when stomach acids move "backwards" through the inferior esophageal sphincter, which manifests symptomatically as "heart burn" (aka, pyrosis).
- The vermiform appendix is susceptible to infection, known as appendicitis, which can spread if it ruptures, an extremely worrisome complication.
- Endoscopy, we examine the upper GI tract (the mouth to the proximal small intestine) – the tube is inserted into the mouth
- Colonoscopy, we examine the lower GI tract (the distal small intestine to the rectum) – the tube is inserted into the anus.