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Histology - Salivary Glands

Salivary Glands
  • Comprise acini that secrete watery and/or mucous solutions with digestive enzymes.
    • These secretions are forced from the acini lumen, through intercalated and striated ducts, and, ultimately, into the oral cavity via main salivary ducts.
  • Myoepithelial cells encircle acini; these cells wrap around serous and mucous acini, and contract to force their secretions from the acini lumen into the ductile system.
  • Striated ducts receive secretions from intercalated ducts; these are distinguished by their striped appearance, which derives from basal interdigitations of cytoplasmic processes.
Parotid Gland
  • Lies in the cheek and is the largest salivary gland
  • Septum = ribbons of connective tissue that divide the glandular tissue into irregular-shaped lobes.
  • The lobular tissue = serous acini, which are clusters of cells that produce a watery substance.
    • At higher magnification, we would see the cytoplasmic zymogen granules that contain digestive enzymes and proenzymes.
Sublingual gland
  • Lies under the tongue.
  • Comprises light-staining mucous acini, which appear cloud-like in this sample.
    • Adipocytes may also be present; they are more prevalent in the glands of older individuals.
Submandibular gland
  • Lies under the lower jaw bone (the mandible)
  • Comprises a mix of light and dark acini
    • Mucous acini with serous demilune caps
Images:
Histology (Mark Braun, MD, & Indiana University: http://medsci.indiana.edu/c602web/602/c602web/toc.htm; http://www.indiana.edu/~anat215/virtualscope2/start.htm)

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