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Cranial Nerves

Functional groups
Somatomotor set
  • CNs 3, 4, 6, 12, and 11 are part of the somatomotor set.
  • They all innervate midline musculature and have midline-lying nuclei.
Solely special sensory set
  • CNs 1, 2, 8 are the solely special sensory set.
  • These CNs purely serve sensory function.
Pharyngeal arch set
  • CNs 5, 7, 9, 10 are the pharyngeal arch set.
  • These nerves all contain numerous functions.
Somatomotor Set
CN 3, oculomotor nerve:
  • Exits the midbrain near midline; midline brainstem strokes often injure this nerve.
  • It innervates several ocular muscles, which are the following extraocular recti muscles: medial, superior, and inferior; it innervates the inferior oblique and levator palpebrae muscles; and it produces pupillary constriction; thus, it serves 4 of the 6 primary eye movements and constricts the pupils.
  • Clinical Correlation: 3rd Nerve Palsy
CN 4, trochlear nerve:
  • Wraps around the outside of the pons (even though it originates from midline of the lower midbrain).
  • CN 4 decussates (crosses midline) as it exits the brainstem contralateral (on the side opposite) to its side of origin – it's the only CN to make this decussation.
  • It innervates the superior oblique, which provides intorsion and depression. If someone has a head tilt, it may be to bring their eyes into alignment from a CN 4 injury.
  • Clinical Correlation: 4th Nerve Palsy
CN 6, abducens nerve:
  • Exits near midline from the pontomedullary junction.
  • It innervates the lateral rectus, which rotates the eye outward.
  • Clinical Correlation: 6th Nerve Palsy
CN 12, hypoglossal nerve:
  • Emerges paracentrally from the mid-medullary level.
  • Just like CNs 3 and 6, CN 12 has a central (midline) course.
  • It provides tongue protrusion.
CN 11, spinal accessory nerve:
  • Emerges laterally from the cervical spinal cord.
    • CN 11 is no longer thought to have additional brainstem origins.
  • It provides head turn and shoulder shrug.
    • Raise your shoulder and feel the action of trapezius, which it innervates.
Solely Special Sensory Set
CN 1, olfactory nerve
  • Serves our sense of smell.
  • The olfactory nerve is the short course of olfactory wiring from olfactory epithelial surface to the olfactory bulb.
CN 2, optic nerve
  • Functions in vision.
    • It's thick because of how much wiring is devoted to vision – most of the posterior brain solely deals with visual processing!
  • The pituitary gland can grow into and injure the optic chiasm.
CN 8, vestibulocochlear nerve
  • Carries hearing (auditory) and balance (sensory) – two separate sensory functions.
Pharyngeal Arch Set
CN 5, trigeminal nerve
  • Provides motor innervation for mastication (chewing).
  • Receives facial sensation.
    • The sensory portion of CN 5 is thick due to the sensitivity of facial sensation.
CN 7, facial nerve
  • Provides facial movement
  • Provides taste sensation from the anterior two-thirds of the tongue.
  • Facial palsy (droop), which is flattening of one side of the face is a common presenting neurologic complaint.
CN 9, glossopharyngeal nerve & CN 10, vagus nerve
  • Learn them together because their actions are similar and most easily remembered when grouped.
As a simplification, both CNs are involved:
  • Swallow
  • Cardio-pulmonary function
  • CN 9 is involved in salivation
  • CN 10 is involved in gut motility.
  • CNs 9 and 10 are carry key autonomic functions.
Mneomnic
On Old Olympus's Towering Top, A Finn And German Viewed Some Hops.
CN 1 – Olfactory (On) CN 2 – Optic (Old) CN 3 – Oculomotor (Olympus) CN 4 – Trochlear (Towering) CN 5 – Trigeminal (Tops) CN 6 – Abducens (A) CN 7 – Facial (Finn) CN 8 – Auditory or Vestibular (aka vestibulocochlear nerve). CN 9 – Glossopharyngeal (German) CN 10 – Vagus (Viewed) CN 11 – Spinal accessory (Some) CN 12 – Hypoglossal (Hops)