Biofilm
- To further secure adherence to the host, and to protect themselves from the immune system and antibiotics, pili and surface adhesins contribute to the formation of biofilms.
- Comprises bacterial cells, in some cases of multiple strains or species, surrounded by matrix. Biofilm formation is an example of a virulence factor regulated by quorum sensing.
–
Dental plaque is an example of a biofilm, which we can see in the image as purple-stained areas.
– Biofilm production by
S. aureus in
endocarditis facilitates the growth of large bacterial vegetations, which can damage the heart or, if they break free, cause
stroke.