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Enzymology: 2. Nomenclature
Oxidoreductases
  • Catalyze electron transfer reactions (oxidation/reduction reactions)
Transferases
  • Catalyze transfer of functional groups to a molecule
Hydrolases
  • Catalyze breakage of bonds by hydrolysis (addition of water)
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Enzymology: 2. Nomenclature

Enzyme Nomenclature
  • Enzyme names are derived from the substrate or the chemical reaction the enzyme catalyzes.
  • Most enzyme names have the suffix "–ase."
Isozymes (aka isoenzymes)
  • Enzymes that catalyze the same reaction but have different amino acids sequences (so they are different proteins).
Enzymes requiring cofactors:
  • An apoenzyme is an enzyme without the cofactor.
  • A holoenzyme is the enzyme and cofactor together.
SIX classes of Enzymes
These enzymes cover every type of enzyme-catalyzed reaction.
  • Oxidoreductases
  • Transferases
  • Hydrolases
  • Lyases
  • Isomerases
  • Ligases

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