Q. You are called to see a 34-year-old female patient admitted yesterday by one of your colleagues for shortness of breath. Staff reports to you that she did well overnight and that her condition has since deteriorated. Upon review of her chart, it is noted that she presented to the emergency department yesterday with complaints of cough, night sweats, and pleuritic chest pain. A chest x-ray performed on admission showed a left pleural effusion, and a subsequent thoracentesis revealed a glucose level of 45 mg/dL, LDH 330 U/L, pleural fluid protein 4.2 g/dL, and serum protein 2.8 mg/dL. A sputum culture for Acid Fast Bacilli (AFB) was negative. Cardiac enzymes were also negative x3, and an EKG performed less than an hour ago showed normal sinus rhythm with no acute changes. On physical examination, she is dyspneic and agitated. Her temperature is 38.0 C, heart rate 85 beats per minute, blood pressure 145/90 mmHg, and oxygen saturation is 87% on 2L O2 via nasal cannula. A Purified Protein Derivative (PPD) placed on her right forearm in the emergency department yesterday demonstrates 18mm of induration. A repeat lateral decubitus chest x-ray today shows a 1 cm left-sided pleural effusion. Which of the following is the most appropriate action?