Q. A 52-year-old man who underwent right total hip replacement two days ago with general anesthesia was admitted to ICU due to mild hypoxemia and uncontrolled hyperglycemia. He receives oxygen by face mask. He also receives insulin, enoxaparin (SC 40 mg/daily), paracetamol (IV 1 g every 12 hours), and hydrocortisone (IV 50 mg every 6 hours). His medical history is significant for rheumatoid arthritis and diabetes mellitus type II. Twenty minutes ago, he suddenly developed dyspnea, tachypnea, and chest pain. He is agitated and has no fever. The chest pain is pleuritic. The right lower extremity is swollen (both thigh and leg) and tender to palpation. The pulse rate is 112/min, respiratory rate is 31/min, and blood pressure is 105/74 mmHg. Percutaneous oxygen saturation is 91%. The body mass index is 29.8 kg/m2. The chest x-ray is negative. Lab tests are only significant for blood sugar 210 mg/dL and D-Dimer 450 ng/mL. Arterial blood gas (ABG) with oxygen mask shows PO2 76 mmHg, PCO2 29 mmHg, and pH 7.48. You ask for a pulmonary CT angiography, and it confirms the diagnosis of pulmonary embolism. What is the best plan for him?