Q. A 72-year-old female patient presents to the emergency department with altered mental status, fever, chills, and dysuria for the last 48 hours. The patient's daughter reports that her mother has been increasingly confused and weak. She has a history of diabetes and hypertension. On physical examination, she appears ill, with a temperature of 38.5°C, heart rate of 120 bpm, respiratory rate of 24 breaths per minute, and blood pressure of 90/60 mmHg. Urinalysis reveals numerous white blood cells and positive nitrites. Lab investigations include a CBC showing a white blood cell count of 22,000/µL with left shift, lactate of 4 mmol/L, and normal liver and kidney function tests. What would be the most appropriate next step in management?