Q. A 23-year-old female from India presents with a persistent cough lingering for a month. The cough is productive, with scanty, sometimes blood-tinged sputum. She also reports low-grade fever, more apparent in the evenings, night sweats, and unintentional weight loss of around 10 lbs. over the last month. She has fatigue and a general feeling of malaise. She denies chest pain, shortness of breath, or recent travel.
On physical examination, she was afebrile with a pulse of 88 beats per minute and a blood pressure of 120/80 mmHg. The chest examination has revealed decreased breath sounds and dullness on percussion at the right upper lobe. The rest of the physical exam was unremarkable.
Lab investigations show a white blood cell count of 12,000/ mm3 with lymphocytic predominance. A chest x-ray shows an area of consolidation in the right upper lobe with mediastinal lymphadenopathy. A sputum smear for acid-fast bacilli was positive, while the culture report is still awaited.
What is the most appropriate next step in managing this patient's condition?