Q. A 40-year-old male, previously healthy, presents to the emergency department complaining of cough with greenish sputum for the past 3 months. The cough is associated with fatigue, weight loss, and night sweats. The patient denies any history of fever, chest pain, hemoptysis, or shortness of breath. He denies any previous medical conditions or surgeries. The patient reports no history of smoking, alcohol consumption, or illicit drug use. He works as a construction worker and has no known exposure to tuberculosis. The patient's symptoms started 3 months ago with a mild cough and greenish sputum. The cough progressively worsened, and he developed fatigue, loss of appetite, and weight loss of approximately 15 pounds over the past 3 months. The patient also reports night sweats but denies any fever, chest pain, hemoptysis, or shortness of breath. He has tried taking over-the-counter cough suppressants, but they were ineffective. He reports being up to date on his immunizations, including the bacille Calmette-Guérin (BCG) vaccine.
On physical examination, the patient is afebrile with a pulse rate of 80 beats/min, blood pressure of 120/70 mm Hg, respiratory rate of 20 breaths/min, and oxygen saturation of 98 percent on room air. The patient appears ill and has a wasted appearance. Chest examination reveals decreased breath sounds over the left upper lobe with dullness on percussion. The remainder of the physical examination is unremarkable.
The patient's initial laboratory investigations show a leukocyte count of 12,000 cells/mm3 with neutrophilic predominance. His erythrocyte sedimentation rate is 65 mm/hour, and his C-reactive protein is 25 mg/L. The patient's chest X-ray (see image) shows left upper lobe consolidation with cavitation. An acid-fast bacilli smear from his sputum is also positive.
Based on the most likely diagnosis, which of the following is the LEAST likely complication?