Q. A 45-year-old female who presents to the emergency department complaining of a fever, fatigue, and muscle pain for the past week. She is a homemaker and does not have any significant medical history. The patient reports that she had a sudden onset of fever and chills about a week ago, which was followed by fatigue and muscle pain. She also complains of headaches and sweating during the night. Despite taking over-the-counter medications, her symptoms have persisted and worsened over the past few days. She denies having any cough, chest pain, abdominal pain, or diarrhea. She reports no recent travel history or exposure to sick individuals.
On physical examination, she is febrile with a temperature of 101.5 degrees Fahrenheit, tachycardic with a heart rate of 110 beats/min, and hypotensive with a blood pressure of 90/60 mm Hg. Her oxygen saturation is 96 percent on room air. Examination of her chest, abdomen, and neurological systems is unremarkable. There is no lymphadenopathy or skin rash noted. You order blood tests, which reveal a leukocytosis with a white blood cell count of 16,000 cells/microliter and a C-reactive protein level of 50 mg/L. Her liver function tests are within normal limits, and urinalysis is negative for any infection. Chest x-ray is normal. You also order serologic tests for Coxiella burnetii. The initial test results showed a high phase I immunoglobulin G titer of 1:2048 and a phase II IgG titer of 1:64, consistent with acute Q fever.
Which of the following treatment options is the best choice for this patient?