Q. A 45-year-old female is admitted with a target lesion on her left leg. She reports noticing the rash three days ago and initially thought it was a mosquito bite. However, the rash progressively increased in size, and she started to experience flu-like symptoms, including headache, fatigue, and muscle aches. The patient has a history of hypertension, which is well controlled on lisinopril. She reports no allergies or previous medical problems. She also denies any recent travel history or exposure to animals. On physical examination, she appears ill and has a temperature of 38.4 degrees Celsius. Assessment of her left posterior lower extremity shows an erythematous, circular rash with a central clearing, consistent with an erythema migrans target lesion (see image). She had several other erythematous macules on her chest and back. Blood tests reveal leukocytosis and elevated liver enzymes. You order Lyme disease serology which comes back positive for both IgG and IgM antibodies. Which of the following statements is NOT true regarding the diagnosis and treatment of this patient?