Q. An 8-year-old male is brought to the hospital by his parents with a history of severe constipation for the past two weeks. The patient reports discomfort and abdominal pain while passing stools. He has only passed stools twice in the past two weeks and both times, the stools were hard and pellet-like. The patient has not experienced any recent changes in diet or lifestyle and denies any associated symptoms such as fever or vomiting. The patient has a history of chronic constipation since early childhood, but this is the first time it has become so severe. He is otherwise healthy with no significant past medical history.
On physical examination, the patient appears uncomfortable with a distended abdomen. Abdominal palpation revealed multiple hard masses consistent with fecal impaction. Digital rectal examination confirms the presence of a large fecal impaction. You order an abdominal X-ray (see image), which shows multiple air-fluid levels consistent with fecal impaction.
Which of the following medications do consensus guidelines recommend as the first-line therapeutic agent for this patient’s condition?