Step 3 - Gastroenterology - Inpatient Medicine

USMLE / COMLEX - Step 3 > Gastroenterology > USMLE/COMLEX 3 - Prep Questions

Q. A 45-year-old male is admitted to the hospital with a chief complaint of severe abdominal pain. The pain has been ongoing for several days and is associated with nausea and vomiting. He also reports 15 pounds of unintentional weight loss over the past six months. On physical examination, the patient is found to have a distended abdomen with tenderness in the lower quadrants. Further evaluation reveals that the patient has a family history of colon cancer, and he has been experiencing similar symptoms for several years. A colonoscopy is performed, and the results show the presence of multiple polyps in his colon (see image). Which of the following statements is NOT true concerning the most likely diagnosis?

Treatment involves radiation and chemotherapy
The disorder results from a mutation in the APC gene on chromosome 5
Sulindac has been shown to reduce the number of adenomas by 50 percent
Celecoxib has demonstrated a 30 percent reduction in adenoma burden
100 percent of untreated patients will develop colorectal cancer
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