Q. A 55-year-old male presented to the emergency department yesterday with chest pain. He underwent a thorough evaluation for a potential myocardial infarction, including electrocardiogram, imaging studies, and serial cardiac markers. All results were negative and the patient was ultimately admitted with a diagnosis of severe gastroesophageal reflux disease. The patient is an auto mechanic and owns his own business. His past medical history is significant for a longstanding history of reflux, obesity, hypertension, and hyperlipidemia. He also has a 40-pack-year history of smoking and drinks alcohol regularly.
The patient underwent endoscopy (see image) and multiple biopsies were taken. The biopsy specimens showed replacement of the normal squamous epithelium of the esophagus at the GE junction by a specialized columnar epithelium with goblet cells. Immunohistochemistry was performed on the specimens, which confirmed the presence of intestinal metaplasia. No dysplasia or malignancy was identified in the biopsy specimens. Staff report the patient did well overnight with no new symptoms or complaints. His symptoms have resolved this morning and you are preparing to send him home. The patient is anxious about the pathology findings and has several questions prior to discharge.
Based on these findings, which of the following statements about the most likely diagnosis is NOT true?