Q. A 65-year-old female comes to the emergency department complaining of chest pressure and shortness of breath for one day. She also reports progressively worsening weakness and fatigue for two days. Prior to her arrival, she developed extreme weakness in all her extremities rendering her unable to move. She screams “I feel like I’m going to die”. She has a history of type 2 diabetes mellitus, hypertension, lupus and hypothyroidism. The patient is currently taking metformin, ramipril, methotrexate and levothyroxine. She also receives subcutaneous insulin before meals. She developed upper respiratory tract infection eight days back and was prescribed trimethoprim-sulfamethoxazole. Her temperature is 38.4°C (101.2 °F), blood pressure is 170/65 mmHg, pulse is 20/min and respiratory rate is 20/min. Respiratory examination was significant for coarse breath sounds bilaterally. Cardiac exam was unremarkable. Neurological examination was unremarkable for focal deficit but significant generalized weakness was noted in all extremities with 2/5 strength. Results of point of care testing performed at the bedside are as follows: Sodium 135 mEq/L Potassium 8.0 mEq/L Troponin I levels <0.10 Which one of the following medications is most likely responsible for her laboratory abnormalities?