Q. A 40-year-old woman was brought to the emergency room by her husband for headache, body rash, and confusion for the past 2 days. He also reports that she had vomited twice and he has given painkillers for headache. Her medical history is significant for systemic lupus erythematosus. She is not on any regular medication. Her temperature is 100°F (37.8°C), heart rate is 100/min, respiratory rate is 14/minute, and blood pressure is 110/70 mm of Hg. On examination, she appears pale and disoriented. Multiple petechiae and purpura are noted on her skin, along with scattered ecchymoses. Neurological examination shows decreased muscle strength and sluggish reflexes. Laboratory studies are shown below. The peripheral blood smear shows abundant schistocytes. What is the next appropriate step in her management?