Q. A 25-year-old man of Mediterranean descent comes to his physician’s office for a routine checkup. He has no significant medical history and is not taking any medications. His temperature is 98.4°F (36.8°C), heart rate is 80/min, respiratory rate is 14/minute, and blood pressure is 120/70 mm of Hg. Physical examination is unremarkable except for mild pallor. Laboratory investigations are shown below. The peripheral blood smear shows marked microcytosis. Hemoglobin electrophoresis shows an HbA2 level of 6.5% and an HbF level of 2%. Genetic testing shows a heterozygous mutation for Beta-thalassemia. What is the most appropriate next step in the management of this patient?