Q. A 55-year-old man comes to his physician’s office for persistent fatigue, low-grade fever, night sweats, and unintentional weight loss of 15 pounds over the past six months. He denies any recent infections or illnesses. His temperature is 99.8°F (37.6°C), heart rate is 100/min, respiratory rate is 14/minute, and blood pressure is 110/70 mm of Hg. Physical examination shows generalized lymphadenopathy. The rest of the examination is normal. Laboratory testing is shown below. An excisional lymph node biopsy is performed. The histopathology report shows uniform nodularity throughout the node with mild variation in the size and shape of the follicles and an absence of Reed-Sternberg cells. What is the next step in the management of this patient?