Q. A 5-year-old previously healthy boy is brought to the pediatrician’s office for a two-week history of fatigue, anorexia, pallor, and easy bruising. His temperature is 99.8°F (37.6°C), heart rate is 100/min, respiratory rate is 14/minute, and blood pressure is 110/70 mm of Hg. Physical examination shows pallor, petechiae on both lower limbs and hepatosplenomegaly. Laboratory results are shown below. The bone marrow biopsy shows large lymphoblasts with prominent nucleoli and light blue cytoplasm. Immunophenotyping is positive for CD19, and CD20. What is the next step in management?

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