Q. A 37-year-old woman visits the outpatient clinic for a blood pressure follow-up. The patient was diagnosed with hypertension a month ago and was started on an angiotensin-converting enzyme inhibitor. Despite adhering to her medications, the patient reports difficult blood pressure control. The patient has no significant medical history. She never smokes; however, she drinks alcohol socially.
Her vital signs show a blood pressure of 160/100 mm Hg, heart rate 75/min, and respiratory rate of 13/min. Clinical examination is significant for carotid bruits. Her laboratory results show hypokalemia.
Which of the following is the most likely pathophysiology of this patient's hypertension?