Q. A 52-year-old woman came to your office for her follow-up. She was diagnosed with rheumatoid arthritis three years ago and has been under treatment with methotrexate and several courses of glucocorticoids. She never had full remission and is currently complaining of joint pain in both hands, knees, and left shoulder, plus more than 30 minutes of post-rest stiffness. She mentions that she has recently developed pallor and shortness of breath during stair climbing. Medical and family histories are not significant other than RA. The examination of hands and knees shows mild swelling with no erythema or warmth. The active range of motions in the hands is slightly limited. The significant lab results are as follows. Blood: WBC 11,200/mm3 * Neutrophils, segmented 27% * Neutrophils, bands 3% * Lymphocytes 66% * Monocytes 4% Hb 10.2 g/dL Mean corpuscular hemoglobin (MCH) 26 pg/cell Mean corpuscular hemoglobin concentration (MCHC) 33% Mean corpuscular volume (MCV) 88 fL Reticulocyte count 0.4% Iron 45 µg/dL Transferrin 180 mg/dl Ferritin 135 ng/mL Serum creatinine 0.8 mg/dL Serum hepcidin level is high. Serum vitamin B12 and folate are normal. Liver function tests are normal. What is the best plan for anemia in her?