Q. A 45-year-old woman presents to the endocrinology clinic with a palpable nodule in her thyroid. She has no significant past medical history and no family history of thyroid disease. On examination, the nodule is firm, mobile and measures approximately 2 cm in diameter. Fine needle aspiration cytology is performed and the results reveal a follicular lesion. Further imaging and biopsy confirm invasion of the thyroid capsule and vasculature.
Genetic studies reveal RAS mutation and PAX8-PPAR-gamma translocations.
What is the most likely diagnosis for the patient's thyroid lesion?