Step 1 - Endocrine System Questions

USMLE / COMLEX - Step 1 > Endocrine System > USMLE/COMLEX 1 - Prep Questions

Q. A 55-year-old male patient with a history of chronic kidney disease and hypertension is admitted to the hospital with complaints of palpitations and muscle weakness. Laboratory tests reveal serum potassium levels of 6.5 mEq/L, confirming hyperkalemia. The patient is started on patiromer. What is the mechanism of action of patiromer in treating hyperkalemia in this patient?

Directly inhibiting K+ channels in the renal tubules, leading to decreased K+ reabsorption.
Blocking aldosterone receptors in the distal tubules, leading to decreased K+ secretion.
Binding K+ in the colon in exchange for other cations like sodium and calcium, leading to increased fecal excretion of K+.
Increasing urinary excretion of K+ through inhibition of the Na+/K+ ATPase pump in the renal tubules.
Increasing the synthesis and release of insulin, leading to decreased serum K+ levels.
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