Q. A 58-year-old construction worker presents to his primary care physician with insidious onset of breathlessness during exertion for the past several months. He has a 30-pack-year smoking history and drinks alcohol occasionally. His family history is significant for heart disease in his father. Upon physical examination, you notice pleural plaques on his chest X-ray. Pulmonary function tests reveal reduced lung volumes and decreased DLCO. His vital signs are: temperature 98.2°F (36.8°C), blood pressure 135/85 mmHg, heart rate 78 beats/min, respiratory rate 18 breaths/min, and oxygen saturation 96% on room air. Based on his presentation, what is the most likely diagnosis?

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