Antiepileptic Drug Therapeutics (Part 2)

Clinical Pharmacology > Neuropsychiatric System > Epilepsy

Q. You take over care for a chronic epileptic patient and see that he is on a very old antiepileptic drug. You decide to wean him off of the medication over the course of 1 - 2 weeks and add a new antiepileptic drug, as a replacement. The patient's sibling calls to say that the patient is extremely agitated and anxious and simply won't calm down; he can't sleep and he is incredibly psychologically distressed. What best explains what happened?

You weaned the patient off of phenytoin too quickly.
You weaned the patient off of carbamazepine too quickly.
You weaned the patient off of phenobarbital too quickly.
You substituted the old seizure drug for lacosamide, which causes agitation.
You substituted the old seizure drug for a benzodiazepine, which causes agitation.
You substituted the old seizure drug for vigabatrin, which causes agitation.
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