Q. A 55-year-old man is brought to the physician by his wife because of strange behavior for the past couple of years. During this time-period, he has become increasingly emotionally labile with sudden anger outbursts and meanness. As well, he has displayed impulsive behavior, with suddenly developing an obsession with buying lottery tickets (which is not normal for him). And he has lost interest in meeting with a group of friends that he has met with routinely for the past 25 years. His vital signs are within normal limits. On clinical examination, his basic orientation is normal and his immediate memory recall is good, but he struggles with thought abstractions and is very tangential, always trying to direct the interview where he wants to take it. As well, he displays difficulty recalling the names of people he should know well. His motor exam and gait are normal. Which would you most likely expect to see on MRI of the Brain imaging?

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