Dementia: Advanced Topics
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Dementia & Encephalopathy
Q. In Creutzfeldt-Jakob disease (CJD), which of the following is true? Note: PrPC = Prion-related Protein Cellular. PrPSc = Prion-related Protein Scrapie.
a
PrPC is alpha-helix-rich and is transformed by PrPSC to PrPSc, which is beta-pleated sheet-rich.
b
PrPSc is alpha-helix-rich and is transformed by PrPC to PrPC, which is beta-pleated sheet-rich.
c
PrPC is beta-pleated sheet-rich and is transformed by PrPSC to PrPSc, which is alpha-helix-rich.
d
PrPSc is beta-pleated sheet-rich and is transformed by PrPC to PrPC, which is alpha-helix-rich.
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