Dementia: Advanced Topics
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Dementia & Encephalopathy
Q. Which of the following best describes the pathophysiology of Creutzfeldt-Jakob disease (CJD)? Note: PrPC = Prion-related Protein Cellular. PrPSc = Prion-related Protein Scrapie.
a
PrPC aggregates to form PrPSc.
b
PrPSc divides into toxic forms of PrPC.
c
PrPSc captures PrPC and refolds it into PrPSc.
d
PrPC captures PrPSc and refolds it into PrPC.
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