Q. A 2-day-old boy is brought to the ER because he has developed a yellowish discoloration of the extremities and the "whites of his eyes are now yellow!" In addition, he is isn't feeding well and he appears listless. On clinical examination, you detect spleen enlargement on palpation and percussion. Laboratory testing demonstrates: * Decreased hemoglobin * Decreased MCV * Normal Iron and ferritin levels * Increased indirect bilirubin The patient is admitted to the hospital and during the admission, genetic testing is sent-out, which ultimately shows a chromosome 16 mutation. What is the most likely cause of this patient's jaundice?