Q. A 26-year-old male presents to the clinic with a 5-month history of persistent upper back pain. He describes the pain as dull and aching, primarily located in the upper thoracic spine region. The pain tends to worsen at night, often disrupting his sleep. He also complains of intermittent low-grade fever, significant fatigue, and occasional chest pain that intensifies during deep respiration. On further questioning, he mentions a stiffness in the back that seems to last for a few hours in the morning but improves with activity throughout the day. Additionally, he occasionally experiences sharp pain radiating to his mid-buttock region.
On physical examination, reduced chest expansion and tenderness over the sacroiliac joints are noted.
What is the most appropriate first-line management of this patient?