Microtubule Structure
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Q. A neuron from a patient with dementia demonstrates intracellular aggregates of hyperphosphorylated tau protein. Which of the following is the primary normal function of tau?
a
ATP-powered movement along actin filaments
b
GTP hydrolysis at the alpha-tubulin N-site
c
Microtubule stabilization and regulation of assembly
d
Formation of axonemal dynein arms
e
Nucleation of microtubules at the basal body
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