Insulin Structure & Physiology
Biochemistry
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Integration of Metabolism
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Hormones and Cell Signaling
Q. Which of the following is the correct pathway for insulin secretion?
a
High blood glucose -> glucose enters Beta cells -> increase in ATP -> ATP inhibit K+ channels -> membrane depolarizes and Ca++ channels open -> influx of Ca++ triggers insulin secretion.
b
High blood glucose -> glucose enters Beta cells -> increase in ATP -> ATP opens K+ channels -> membrane hyperpolarizes and Ca++ channels open -> influx of Ca++ triggers insulin secretion.
c
High blood glucose -> glucose enters alpha cells -> increase in ATP -> ATP inhibit Ca++ channels -> membrane hyperpolarizes and K+ channels open -> efflux of K+ triggers insulin secretion.
d
High blood glucose -> glucose enters alpha cells -> increase in ATP -> ATP inhibit K+ channels -> membrane depolarizes and Ca++ channels open -> influx of Ca++ triggers insulin secretion.
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