USMLE/COMLEX - Step 2 - Idiopathic Pulmonary Fibrosis

USMLE/COMLEX - Step 2 - Idiopathic Pulmonary Fibrosis
Pathophysiology
Inflammation and/or fibrosis of the interstitum of the lung
Etiologies
Medications such as amiodarone Asbestos Polymyositis/dermatomyositis Vasculitis CREST syndrome Sarcoidosis
Symptoms
Shallow breathing Chronic nonproductive cough Dyspnea
Diagnostics
Chest x-ray is the best initial test High resolution CT scan will show honeycombing pattern indicating severe stage Pulmonary function test Biopsy is most accurate test
Treatment
Corticosteroids Antifibrotic agents such as pirfenidone and nintedanib Lung transplant