USMLE/COMLEX - Step 2 - Anaphylaxis (Respiratory Effects)
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Pathophysiology
Antigen cross-links preformed surface-bound IgE on mast cells and basophils, triggering the release of histamine
Etiologies
Food allergy
Bee sting
Symptoms
Difficulty breathing
Hypotension
Hives
Treatment
Intramuscular epinephrine
Antihistamines
IV fluids
Airway support