Two examples of hemangiopericytoma (HPC): one invading the left petrous ridge and the other within the right insula.
Classic features of HPC: parasagittal location and large tortuous vessels are not demonstrated here.
Hemangiopericytoma
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Hemangiopericytoma
- Mesenchymal (mesodermal) tumor that is dural-based, often parsagittal/falcine.
- They have solid and cystic components and characteristically have extensive tortuous (cork-screw) vasculature (prominent flow voids on MRI or tortuous vessels on angiography).
- Classic pathologic findings:
- Randomly oriented spindle cells in a "patternless pattern" with scant cytoplasm.
- Thin-walled vascular spaces called "staghorn" vasculature.
References
- Adesina, Adekunle M., Tarik Tihan, Christine E. Fuller, and Tina Young Poussaint. Atlas of Pediatric Brain Tumors. Springer, 2016.
- Gray, Frangoise, Charles Duyckaerts, and Umberto De Girolami. Escourolle and Poirier’s Manual of Basic Neuropathology. OUP USA, 2013.
- Tonn, Jörg-Christian, Manfred Westphal, and J. T. Rutka. Oncology of CNS Tumors. Springer Science & Business Media, 2010.
- Yachnis, Anthony T., and Marie L. Rivera-Zengotita. Neuropathology E-Book: A Volume in the High Yield Pathology Series. Elsevier Health Sciences, 2012.