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Pneumonia for the Nurse Practitioner Licensing Exam
Etiology
  • Bacterial Pathogens:
    • Streptococcus pneumoniae: The most common cause of community-acquired pneumonia (CAP), presenting with fever, productive cough, and pleuritic chest pain.
    • Haemophilus influenzae: Frequently seen in patients with chronic obstructive pulmonary disease (COPD).
    • Mycoplasma pneumoniae: Causes atypical pneumonia, often in younger patients, with dry cough, low-grade fever, and extrapulmonary symptoms (e.g., rash).
    • Legionella pneumophila: Associated with contaminated water sources, presenting with pneumonia, gastrointestinal symptoms, and hyponatremia.
  • Viral Pathogens:
    • Influenza virus: A common viral cause of pneumonia, especially during flu season.
    • Respiratory syncytial virus (RSV): Affects infants and older adults.
    • SARS-CoV-2: Causes pneumonia in the context of COVID-19, which can progress to acute respiratory distress syndrome (ARDS).
  • Aspiration Pneumonia:
    • Occurs when oropharyngeal contents are aspirated into the lungs, often seen in patients with altered consciousness or swallowing disorders.
Clinical Features
  • Typical Pneumonia:
    • Sudden onset of high fever, productive cough with purulent sputum, pleuritic chest pain, and dyspnea. Physical exam may reveal crackles, bronchial breath sounds, and dullness to percussion.
  • Atypical Pneumonia:
    • Gradual onset of dry cough, low-grade fever, and extrapulmonary symptoms such as headache, myalgias, and fatigue.
  • Aspiration Pneumonia:
    • Often affects the right lower lobe and presents with fever, cough, and foul-smelling sputum.
Diagnosis
  • Chest X-ray:
    • Shows lobar consolidation in bacterial pneumonia or diffuse interstitial infiltrates in atypical or viral pneumonia.
  • Microbiological Testing:
    • Sputum Gram stain and culture for bacterial identification.
    • Urinary antigen tests for S. pneumoniae and Legionella.
Management
  • Outpatient Antibiotics:
    • First-line treatment includes amoxicillin, macrolides (e.g., azithromycin), or doxycycline.
  • Inpatient Management:
    • For severe CAP, use ceftriaxone plus a macrolide or a fluoroquinolone.
    • Oxygen therapy for hypoxia.
Prevention
  • Vaccination:
    • Pneumococcal vaccines (PCV13, PPSV23) for adults over 65 or those with chronic conditions.
    • Annual influenza vaccination.
Key Points
  • Streptococcus pneumoniae is the most common cause of community-acquired pneumonia, presenting with fever, productive cough, and pleuritic chest pain.
  • Atypical pneumonia presents with milder respiratory symptoms and extrapulmonary manifestations.
  • Diagnosis is confirmed with chest X-ray, showing lobar consolidation or diffuse infiltrates.
  • Empiric antibiotics include amoxicillin, macrolides, or fluoroquinolones depending on severity.
  • Prevention includes pneumococcal and influenza vaccination.

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