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The Perforant Pathway

    * The key intra-hippocampal circuitry (so-named because the entorhinal cortex projects through (perforates) the subiculum).
  • Whereas most cortical projections are bidirectional, the perforant pathway follows a specific unidirectional progression.
Steps
  • The dentate gyrus -> CA3 -> CA1 (via Schaffer collaterals) -> subiculum