HSV Type 1 with profound temporal lobe involvement, ultimately causing bilateral amygdala destruction and resulting in Klüver Bucy syndrome.
Klüver Bucy Syndrome
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- * Bilateral amygdala destruction results in Klüver Bucy syndrome, which involves, most prominently, social tameness mixed with a loss of avoidance, manifesting with hypermetamorphosis (the incessant exploration of objects within the environment), hyperorality, visual agnosia, and hypersexuality.
- Klüver Bucy syndrome was first described from the effects of bilateral amygdala and hippocampal destruction in monkeys, but it is a rare complication of a variety of naturally occurring illnesses in humans, including herpes simplex encephalitis, frontotemporal lobar dementia, and anoxicischemic lesions in the bilateral anterior medial temporal lobes.