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MRI Characteristics of Heme Products

Hemorrhage on MRI: Stages of Hemosiderin
Hyperacute < 24hrs
  • Oxyhemoglobin (intracellular)
Acute ~ 1 - 3 days
  • Deoxyhemoglobin (intracellular)
Early Subacute: 3 - 7 days
  • Methehemoglobin (intracellular)
Late Subacute > 7 days
  • Methehemoglobin (extracellular)
Chronic > 14 days
  • Hemosiderin
Simplification of MRI Findings
Hyperacute/Acute
  • T1 - Isointense
T2 - Bright (hyperacute blood may be isointense on T2*).
  • GRE - Black in periphery of hematoma
Subacute
  • T1 - Bright
  • T2 - Isointense
  • GRE - Black expands inward
Chronic
  • T1 - Dark
  • T2 - Dark
  • GRE - Dark