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Intraparenchymal Hematoma

Intraparenchymal hemorrhage refers bleeding within the cerebrum, itself, and has a 30-day mortality risk of approximately 50% with half of patients dying in the first 24 hours.
Modifiable Risk Factors include:
  • Hypertension
  • Alcohol & Drug Use
  • Atherosclerosis
  • Anticoagulants
Pathophysiology:
  • In hypertensive vaculopathy, there are microscopic degenerative changes in the walls of small vessels over time that eventually result in hemorrhage, whereas in cerebral amyloid angiopathy (a disease of the elderly) amyloid-beta peptide lines the walls of small vessels and leads to rupture.
The most common site of intracerebral hemorrhage:
  • The Basal Ganglia.

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