Dorsal Midbrain Syndrome (aka Parinaud Syndrome)
Manifestations of Dorsal Midbrain Syndrome
- Upgaze palsy with convergence-retraction nystagmus
- Meaning when the patient attempts to look up, there is convergent/retractory episodic jerking.
- Eyelid retraction
- Light-near dissociation
- Meaning, the pupils do NOT respond to light but do constrict to near response.
Common Causes
Compressive:
- Pineal Tumors
- Hemorrhages with dorsal midbrain compression
Non-compressive:
- MS plaques
- Dorsal midbrain ischemic strokes
- Neuroinfectious causes