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Sensory Receptors - Nerve Endings

Overview
Major Sensory Receptor Types
There are six major forms of sensory receptors (from superficial to deep*):
    • Free nerve endings
    • Merkel cells
    • Meissner corpuscles
    • Ruffini corpuscles & Krause end bulbs
    • Pacinian corpuscles
Major Classes of Sensory Receptors
  • There are three major classes of sensory receptors:
    • Mechanoreceptors detect mechanical deformation
    • Nociceptors detect pain
    • Thermoreceptors detect temperature
Sensory Receptors by Location within the skin
EPIDERMIS
Free nerve endings
  • Unmyelinated nerve endings.
  • Detect pain and temperature.
BASAL EPIDERMIS
Merkel cells
  • Discs at the ends of unencapsulated nerve fibers.
  • Detect tactile sensation: light touch/hair movement.
SUPERFICIAL DERMIS
Meissner corpuscles (aka tactile corpuscles)
  • Elliptical shaped.
  • Lie perpendicular to the epidermis, within the dermal papillae.
  • Detect light touch; hence, "tactile corpuscle".
DERMIS
Ruffini corpuscles
  • Detect pressure.
Krause end bulbs
  • Detect pressure and low-frequency vibration.
DEEP DERMIS & HYPODERMIS
Pacinian corpuscles (aka lamellated corpuscles)
  • Pacinian corpuscles are large and oval-shaped with a very characteristic concentric, lamellated histological appearance.
  • They are encapsulated mechanoreceptors that detect touch, pressure, vibration.
    • Capsule distortion works to amplify the signal of a mechanical stimulus.