Here are key facts for
NCLEX from the
Small Vessel Vasculitis tutorial, as well as points of interest at the end of this document that are not directly addressed in this tutorial but should help you prepare for the boards. See the
tutorial notes for further details and relevant links.
General Concepts of Vasculitis
1.
Vasculitis is
inflammation of blood vessels leading to
ischemia,
necrosis, and
organ damage.
2. Common general symptoms include
fever, fatigue, weight loss, joint pain, and
skin changes (especially
palpable purpura).
3.
Initial treatment often includes
high-dose corticosteroids to reduce inflammation and prevent complications.
4.
Nursing priorities focus on monitoring for organ dysfunction (e.g., lungs, kidneys) and preventing infection during immunosuppressive therapy.
Specific Small Vessel Vasculitides
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Granulomatosis with Polyangiitis (GPA)
1. Affects
nose, lungs, and kidneys.
2. Symptoms:
- Sinusitis, nasal crusting, nosebleeds.
- Cough, shortness of breath, hemoptysis.
- Kidney damage (hematuria, elevated creatinine).
- Skin signs like purpura.
3. Nursing role:
- Monitor for respiratory distress.
- Watch for signs of kidney failure.
- Support corticosteroid administration and infection prevention.
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Eosinophilic Granulomatosis with Polyangiitis (EGPA)
4. Typically seen in patients with
asthma and
allergic symptoms.
5. Symptoms:
- Severe asthma attacks.
- Peripheral neuropathy (weakness, numbness).
- Cardiac symptoms (chest pain, heart failure signs).
6. Nursing role:
- Prioritize airway management.
- Monitor heart function closely.
- Watch for new neurologic deficits.
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Microscopic Polyangiitis (MPA)
7. Symptoms:
- Rapid kidney decline (RPGN).
- Purpura on skin.
- Possible pulmonary hemorrhage (coughing up blood).
8. Nursing role:
- Monitor respiratory and renal function.
- Early recognition of hemoptysis is critical.
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IgA Vasculitis (Henoch-Schönlein Purpura)
9. Most common in
children.
10. Symptoms:
- Palpable purpura (especially on buttocks and legs).
- Abdominal pain, GI bleeding.
- Joint pain.
- Blood in urine (hematuria).
11. Nursing care:
- Monitor for signs of kidney damage.
- Educate parents that this usually resolves but may need monitoring if kidney involvement is severe.
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Cryoglobulinemia
12. Associated with
hepatitis C infection.
13. Symptoms:
- Purpura.
- Joint pains.
- Kidney issues (hematuria, proteinuria).
14. Nursing care:
- Monitor for kidney problems.
- Help coordinate antiviral therapy for Hepatitis C.
- Monitor for cold-induced symptoms (cryoglobulins precipitate in cold).
Nursing Actions Across All Vasculitides
1.
Monitor for systemic signs of worsening disease:
- Decreased urine output.
- New respiratory symptoms.
- Severe abdominal pain or GI bleeding.
2.
Administer corticosteroids as ordered and monitor for
side effects:
- Blood sugar elevation.
- Infection (masking early signs of sepsis).
- Osteoporosis prevention strategies (calcium and vitamin D).
3.
Educate patients about:
- The importance of infection prevention.
- Adherence to medications even after symptoms improve.
- Monitoring and reporting any new organ-related symptoms (e.g., hematuria, chest pain, dyspnea).
4.
Protect patients from exposure to cold in cryoglobulinemia to avoid symptom exacerbation.
5.
Prepare patients and families for possible biopsy procedures (skin, kidney) if needed for diagnosis confirmation.