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Metronidazole

Metronidazole
  • Most common uses
– Anaerobes Helicobacter pylori Gardnerella vaginalis Clostridium difficile – Also used to treat some parasitic infections
  • Mechanism of Action
– Produces free radical metabolites that damage bacterial DNA
  • Adverse effects
– Gastrointestinal upset – Metallic taste – Disulfiram-like reaction when combined with alcohol