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Metronidazole
Metronidazole
Most common uses
– Anaerobes
Helicobacter pylori
Gardnerella vaginalis
Clostridium difficile
– Also used to treat some parasitic infections
Mechanism of Action
– Produces free radical metabolites that damage bacterial DNA
Adverse effects
– Gastrointestinal upset – Metallic taste – Disulfiram-like reaction when combined with alcohol
Related Tutorials
Antimetabolites and DNA disruptors