Back
medical & biological sciences
All Access Pass - 1 FREE Month!
Institutional email required, no credit card necessary.
FREE ONE-MONTH ACCESS
Institutional (.edu or .org) Email Required
Register Now!
No institutional email?
Start your
1-week free trial
, now!
- or -
Log in through OpenAthens
Macrolides
Macrolides: Azithromycin, Erythromycin, and Clarithromycin
Most common uses
Broad-spectrum – Gram-positive bacteria –
Neisseria
–
Legionella
–
Mycoplasma
–
Chlamydiae
–
Treponema
– Clarithromycin and Azithromycin are effective against some
Mycobacteria
.
Mechanism of Action
– Binds the 50S subunit Block translocation and protein synthesis
Adverse effects
– Gastrointestinal upset due to increased motility –
QT prolongation
– Hepatotoxicity
Related Tutorials
Antibiotics Mechanisms
Antibiotics: Ribosomes