Dapsone

Dapsone
  • Most common uses
Mycobacteria: Leprosy, dermatitis herpetiformis, and some other skin conditions.
  • Mechanism of Action
– Inhibits Mycobacteria folic acid synthesis via inhibition of dihydropteroate synthase.
  • Adverse effects of Sulfonamides
– Hemolytic anemia, particularly in individuals with G6PD deficiencies.