medical & biological sciences

Ganciclovir

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Ganciclovir

Ganciclovir

Valganiciclovir is its prodrug
Ganiciclovir is administered intravenously or orally
Used to treat

– Cytomegalovirus infections (retinitis, pneumonia, and esophagitis) May be used as prophylaxis in In transplant recipients

Can be used, but is not preferred, for:

– Herpes Simplex Virus – Herpes Zoster Virus – Epstein-Barr Virus – Human Herpes Virus 6

Ganciclovir is a guanosine analogue that inhibits viral DNA synthesis

However, it is more toxic than acyclovir, and is associated with bone marrow suppression* and, as a result, leukopenia and thrombocytopenia.

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