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Foscarnet

Foscarnet
  • Administered intravenously
  • Treats:
Cytomegalovirus infections, specifically those that are Ganciclovir-resistant and/or present in AIDS patients – Acyclovir-resistant Herpes Simplex Virus and Varicella-Zoster virusHuman Herpes Virus 6
  • Foscarnet is a pyrophosphate analogue that inhibits viral DNA replication
  • Potentially nephrotoxic, and is associated in anemia in AIDS patients, as well as serum electrolyte changes (such as hypocalcemia and hypomagnesemia)