Foscarnet
- Administered intravenously
- Treats:
–
Cytomegalovirus infections, specifically those that are Ganciclovir-resistant and/or present in AIDS patients
– Acyclovir-resistant
Herpes Simplex Virus and
Varicella-Zoster virus
–
Human Herpes Virus 6
- Foscarnet is a pyrophosphate analogue that inhibits viral DNA replication
- Potentially nephrotoxic, and is associated in anemia in AIDS patients, as well as serum electrolyte changes (such as hypocalcemia and hypomagnesemia)