Gastric Glands

Chemical digestion in the stomach is achieved by secretions from oxyntic and pyloric glands that break down proteins. Oxyntic glands are found in the body of the stomach, and contain chief and parietal cells.

• Chief cells secrete pepsinogen.
• Parietal cells secrete HCL & Intrinsic factor.

Pyloric glands are found in the stomach antrum; they contain mucous cells and G-cells.

• Mucous cells secrete bicarbonate-rich mucus, which protects stomach lining from acids.
• G-cells secrete gastrin, which stimulates parietal cell secretion of HCL.